Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.49 |
| ▸ | PDE4A | P27815 | 18/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8264832 | 0.89 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL8263537 | 0.86 | PDE4D (0.52) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL84871 | 0.85 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL84870 | 0.85 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL3873066 | 0.85 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL7130963 | 0.82 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL74892 | 0.81 | HDAC1 (0.46) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5025240 | 0.80 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL5022391 | 0.77 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL7122581 | 0.75 | PDE4B (0.53) | PDE4DPDE4APDE4BPDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006064355-A2 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-06-22 | — | — | WO | disclosed |