Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.53 |
| ▸ | PDE4A | P27815 | 16/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131196 | 0.85 | CNR1 (0.45) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8264832 | 0.85 | PDE4D (0.47) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL7130963 | 0.85 | PDE4D (0.48) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL5022381 | 0.83 | PDE4D (0.53) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7176265 | 0.82 | CNR1 (0.43) | — | |
| SCHEMBL5017961 | 0.82 | PDE4B (0.51) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7129686 | 0.81 | FABP4 (0.45) | — | |
| SCHEMBL73107 | 0.81 | PDE4D (0.43) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL84871 | 0.75 | PDE4D (0.47) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL8263103 | 0.75 | PDE4D (0.49) | PDE4BPDE4DPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | claimed |
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |