Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 10/20 | 0.47 |
| ▸ | CTSA | P10619 | 3/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766505 | 0.94 | IL2 (0.53) | IL2RAB9ASTIM1ORAI1FFAR4 | |
| SCHEMBL2893809 | 0.85 | IL2 (0.45) | IL2RAB9ASTIM1ORAI1 | |
| SCHEMBL8257121 | 0.83 | STIM1 (0.61) | IL2RAB9ASTIM1ORAI1ORAI2 | |
| SCHEMBL4761818 | 0.79 | ORAI1 (0.65) | RAB9ASTIM1ORAI1FFAR4 | |
| SCHEMBL4761819 | 0.78 | STIM1 (0.50) | CTSASTIM1ORAI1FFAR4 | |
| SCHEMBL5556022 | 0.76 | STIM1 (0.53) | IL2RAB9ASTIM1ORAI1ORAI2 | |
| SCHEMBL15528440 | 0.76 | IL2 (0.71) | IL2RAB9ASTIM1ORAI1 | |
| SCHEMBL8296803 | 0.75 | IL2 (0.56) | IL2RAB9ASTIM1ORAI1 | |
| SCHEMBL2308121 | 0.73 | IL2 (0.58) | IL2RAB9A | |
| SCHEMBL12093752 | 0.72 | IL2 (0.57) | IL2RAB9ASTIM1ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083477-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-10 | — | — | WO | disclosed |