Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897732 | 0.94 | MEN1 (0.42) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL4574895 | 0.94 | MEN1 (0.42) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL14045484 | 0.93 | ABCB11 (0.40) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL4892474 | 0.92 | ABCB11 (0.39) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL4903835 | 0.92 | ABCB11 (0.39) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL4892652 | 0.91 | MEN1 (0.48) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL4892699 | 0.91 | ADRB3 (0.43) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL4895738 | 0.91 | ADRB3 (0.43) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL4923480 | 0.91 | MEN1 (0.48) | ATF4ABCB11ADRB3ADRB1ADRB2 | |
| SCHEMBL14046032 | 0.91 | ABCB11 (0.39) | ATF4ABCB11ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060122-A2 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |