Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8264379 | 0.94 | REN (0.42) | RENCYP3A4 | |
| SCHEMBL8265425 | 0.94 | REN (0.46) | RENCYP3A4 | |
| SCHEMBL8265243 | 0.93 | REN (0.44) | RENCYP3A4 | |
| SCHEMBL8264366 | 0.92 | REN (0.43) | RENCYP3A4 | |
| SCHEMBL8262833 | 0.92 | REN (0.45) | RENCYP3A4 | |
| SCHEMBL13490906 | 0.92 | CYP3A4 (0.46) | RENCYP3A4 | |
| SCHEMBL8264361 | 0.91 | REN (0.43) | RENCYP3A4 | |
| SCHEMBL8264289 | 0.91 | REN (0.43) | RENCYP3A4 | |
| SCHEMBL8262863 | 0.90 | REN (0.42) | RENCYP3A4 | |
| SCHEMBL8264371 | 0.90 | REN (0.44) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074924-A1 | 3,4,(5)-SUBSTITUTED TETRAHVDROPYRIDINES | NOVARTIS AG (CH) | 2006-07-20 | — | — | WO | disclosed |