Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 18/20 | 0.65 |
| ▸ | CASP7 | P55210 | 9/20 | 0.65 |
| ▸ | CASP9 | P55211 | 4/20 | 0.65 |
| ▸ | CASP1 | P29466 | 7/20 | 0.64 |
| ▸ | CASP2 | P42575 | 2/20 | 0.61 |
| ▸ | CASP4 | P49662 | 2/20 | 0.61 |
| ▸ | CASP6 | P55212 | 2/20 | 0.61 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535570 | 0.83 | CASP3 (0.76) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL6535574 | 0.83 | CASP3 (0.76) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL6535733 | 0.82 | CASP3 (0.74) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL13925543 | 0.82 | CASP3 (0.78) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL6535888 | 0.82 | CASP3 (0.74) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL5332434 | 0.79 | CASP3 (1.00) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL1092156 | 0.79 | CASP3 (1.00) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL6535354 | 0.79 | CASP3 (1.00) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL1092160 | 0.79 | CASP3 (1.00) | CASP3CASP7CASP9CASP1CASP2 | |
| SCHEMBL3681388 | 0.79 | CASP3 (1.00) | CASP3CASP7CASP9CASP1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074799-A2 | 5-PYRROLIDINYLSULFONYL ISATIN DERIVATIVES | Universitätsklinikum Münster (DE) | 2006-07-20 | — | — | WO | disclosed |