Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 16/20 | 0.67 |
| ▸ | CASP7 | P55210 | 16/20 | 0.67 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925541 | 0.83 | CASP3 (0.78) | CASP3CASP7CASP1CASP6 | |
| SCHEMBL15029242 | 0.81 | CASP3 (1.00) | CASP3CASP7CASP1 | |
| SCHEMBL5184400 | 0.81 | CASP3 (1.00) | CASP3CASP7CASP1 | |
| SCHEMBL6535822 | 0.77 | CASP3 (0.70) | CASP3CASP7CASP1CASP6 | |
| SCHEMBL13925501 | 0.77 | CASP3 (1.00) | CASP3CASP7CASP1CASP6 | |
| SCHEMBL4156846 | 0.77 | CASP3 (1.00) | CASP3CASP7CASP1CASP6 | |
| SCHEMBL6535823 | 0.77 | CASP3 (0.70) | CASP3CASP7CASP1CASP6 | |
| SCHEMBL4156851 | 0.77 | CASP3 (1.00) | CASP3CASP7CASP1CASP6 | |
| SCHEMBL6535698 | 0.76 | CASP3 (0.69) | CASP3CASP7CASP1CASP6 | |
| SCHEMBL6535695 | 0.76 | CASP3 (0.69) | CASP3CASP7CASP1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074799-A2 | 5-PYRROLIDINYLSULFONYL ISATIN DERIVATIVES | Universitätsklinikum Münster (DE) | 2006-07-20 | — | — | WO | disclosed |