SCHEMBL8264178

SCHEMBL8264178

Cc1cccc(C2=CCN(C)CC2)c1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
QDPR P09417 3/20 0.59
SLC6A4 P31645 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16862164 0.83 QDPR (0.67) QDPRSLC6A4
SCHEMBL50923 0.83 QDPR (0.67) QDPRSLC6A4
SCHEMBL16915221 0.83 QDPR (0.56) QDPRSLC6A4
SCHEMBL13126339 0.83 QDPR (0.56) QDPRSLC6A4
SCHEMBL8266073 0.83 QDPR (0.56) QDPR
SCHEMBL11558057 0.83 QDPR (0.56) QDPRSLC6A4
Ammonia Solution, Strong SCHEMBL15875021 0.82 QDPR (0.65) QDPRSLC6A4
Bromide SCHEMBL11557389 0.82 QDPR (0.65) QDPRSLC6A4
Hydrochloric Acid SCHEMBL1148906 0.82 QDPR (0.65) QDPRSLC6A4
SCHEMBL5542027 0.81 QDPR (0.58) QDPRSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2177518-A1 Organic compounds Novartis AG (CH) 2010-04-21 EP disclosed
EP-1833816-B1 SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS NOVARTIS AG (CH) 2009-11-11 EP disclosed
WO-2006069788-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2006-07-06 WO disclosed
US-4132710-A DIURETICS, ANOREXICS, ANTIDEPRESSANTS, ANTICONVULSANTS, & ANTIHYPERTENSIVE AGENTS AYERST, MCKENNA AND HARRISON, LTD. (CA) 1979-01-02 US disclosed