SCHEMBL826419

SCHEMBL826419

O=S(=O)(O)c1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA12 O43570 3/20 0.41
CA3 P07451 3/20 0.41
CA4 P22748 3/20 0.41
CA6 P23280 3/20 0.41
CA5A P35218 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
CA5B Q9Y2D0 3/20 0.41
CA13 Q8N1Q1 2/20 0.41
CISD1 Q9NZ45 1/20 0.41
CNR1 P21554 1/20 0.40
GUSB P08236 1/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
PGR P06401 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410051 1.00 L3MBTL1 (0.44) L3MBTL1CA1CA2CA12CA3
Hydrochloric Acid SCHEMBL27610010 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
SCHEMBL13278133 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
SCHEMBL1997081 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
SCHEMBL13277972 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
SCHEMBL13277223 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
Potassium SCHEMBL29834163 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
SCHEMBL13277813 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
SCHEMBL2000643 0.97 L3MBTL1 (0.42) L3MBTL1CA1CA2CA12CA3
SCHEMBL10827572 0.95 L3MBTL1 (0.41) L3MBTL1CA1CA2CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114605310-B Synthesis method of aza five-membered ring and three-membered ring carboxylic ester derivative and salt thereof 都创(上海)医药科技股份有限公司 2024-05-07 CN claimed
CN-115232102-B Preparation method and production device of lactide 中国科学院长春应用化学研究所 2024-02-13 CN claimed
CN-117143443-A Flame-retardant polycarbonate composition and preparation method and application thereof 金发科技股份有限公司 2023-12-01 CN claimed
CN-113861651-B Polycarbonate composition and preparation method and application thereof 天津金发新材料有限公司 2023-05-09 CN claimed
CN-113149870-B Synthetic method of 2,4,5-trichlorobenzene sulfonic acid 武汉青江化工黄冈有限公司 2023-03-24 CN claimed
CN-115232102-A Preparation method and production device of lactide 中国科学院长春应用化学研究所 2022-10-25 CN claimed
CN-113861651-A Polycarbonate composition and preparation method and application thereof 天津金发新材料有限公司 2021-12-31 CN claimed
CN-113149870-A Synthesis method of 2,4, 5-trichlorobenzene sulfonic acid 武汉青江化工黄冈有限公司 2021-07-23 CN claimed
EP-3365168-B1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC (US) 2021-06-30 EP claimed
US-20210171437-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO VERA THERAPEUTICS INC (US) 2021-06-10 US claimed
EP-0615533-A1 FLAME RESISTANT THERMOPLASTIC BLENDS HAVING REDUCED DRIPPAGE GENERAL ELECTRIC COMPANY (US) 1994-09-21 EP claimed
WO-1994007956-A1 FLAME RESISTANT THERMOPLASTIC BLENDS HAVING REDUCED DRIPPAGE GENERAL ELECTRIC COMPANY (US) 1994-04-14 WO claimed
EP-0496396-A2 2,5-dichlorophenylthioglycolic acid derivative and method for its production SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1992-07-29 EP claimed
US-5068405-A Famotidine intermediates and their preparation DELMAR CHEMICALS INC. (CA) 1991-11-26 US claimed
CN-1042923-A The preparation of polyketane polymers SHELL INT RESEARCH (NL) 1990-06-13 CN claimed
EP-0224292-B1 PROCESS FOR THE PREPARATION OF ORGANIC ISOCYANATES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-04-11 EP claimed
EP-0319083-A2 Polyketone polymer preparation SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-06-07 EP claimed
EP-0224292-A1 Process for the preparation of organic isocyanates SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-06-03 EP claimed
US-4670610-A Preparation of 2,5-dichlorophenol SANDOZ, INC. (CH) 1987-06-02 US claimed
US-4171459-A Manufacture of α-naphthol BASF AKTIENGESELLSCHAFT (DE) 1979-10-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171437-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO TARBP1, TIA1, SSB L3MBTL1 983/4885CA1 145/4885CA2 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.