Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 4/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107704 | 0.85 | KDM4C (0.43) | KDM4CKMT2AMEN1L3MBTL1CREBBP | |
| SCHEMBL13490826 | 0.85 | KDM4C (0.43) | KDM4CKMT2AMEN1L3MBTL1CREBBP | |
| SCHEMBL18355699 | 0.83 | TACR1 (0.46) | KDM4CKMT2AMEN1CREBBPEP300 | |
| SCHEMBL4574560 | 0.82 | KDM4C (0.41) | KDM4CKMT2AMEN1L3MBTL1CREBBP | |
| SCHEMBL2006340 | 0.82 | TACR1 (0.45) | KDM4CKMT2AMEN1L3MBTL1CREBBP | |
| SCHEMBL13787407 | 0.82 | KDM4C (0.43) | KDM4CKMT2AMEN1L3MBTL1CREBBP | |
| SCHEMBL8887331 | 0.80 | KDM4C (0.41) | KDM4CKMT2AMEN1L3MBTL1CREBBP | |
| SCHEMBL23662493 | 0.79 | KDM4C (0.41) | KDM4CKMT2AMEN1L3MBTL1CREBBP | |
| SCHEMBL8321854 | 0.79 | TACR1 (0.47) | KDM4CKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29866511 | 0.79 | KDM4C (0.41) | KDM4CKMT2AMEN1L3MBTL1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074924-A1 | 3,4,(5)-SUBSTITUTED TETRAHVDROPYRIDINES | NOVARTIS AG (CH) | 2006-07-20 | — | — | WO | disclosed |