SCHEMBL826422

SCHEMBL826422

Nc1cc(O)c(Cl)cc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.46
TSHR P16473 3/20 0.46
HPGD P15428 2/20 0.46
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
ALDH1A1 P00352 4/20 0.38
CA9 Q16790 3/20 0.38
CA12 O43570 2/20 0.38
CA7 P43166 2/20 0.38
CA14 Q9ULX7 2/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 1/20 0.38
THRB P10828 1/20 0.37
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
ESR2 Q92731 2/20 0.33
CA4 P22748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8894373 0.98 HSD17B10 (0.44) HSD17B10TSHRHPGDCA1CA2
SCHEMBL4034317 0.91 HSD17B10 (0.46) HSD17B10TSHRHPGDCA1CA2
SCHEMBL9386078 0.88 HPGD (0.37) HSD17B10TSHRHPGDCA1CA2
SCHEMBL31163154 0.81 GAA (0.50) HSD17B10TSHRHPGDCA1CA2
SCHEMBL12786927 0.81 GAA (0.50) HSD17B10TSHRHPGDCA1CA2
SCHEMBL1477638 0.79 GAA (0.53) TSHRCA1CA2ALDH1A1CA9
SCHEMBL18893969 0.79 HSD17B10 (0.55) HSD17B10TSHRHPGDCA1CA2
SCHEMBL14578394 0.79 GAA (0.53) TSHRCA1CA2ALDH1A1CA9
SCHEMBL30573328 0.79 GAA (0.53) TSHRCA1CA2ALDH1A1CA9
SCHEMBL17000444 0.79 HSD17B10 (0.55) HSD17B10TSHRHPGDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626370-B1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL CO (JP) 1998-02-11 EP claimed
EP-0554894-B1 Imine derivatives and process for production thereof SUMITOMO CHEMICAL CO (JP) 1996-02-07 EP claimed
EP-0626370-A1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-11-30 EP claimed
EP-0554894-A2 Imine derivatives and process for production thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-08-11 EP claimed
JP-5286912-A None JP disclosed
JP-5213844-A None JP disclosed
JP-5262704-A None JP disclosed
JP-6092913-A None JP disclosed
WO-2025103931-A1 SUBSTITUTED CYCLOPROPYLOXYPHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
CN-113365981-B Process for producing pyridone compound 住友化学株式会社 2024-11-08 CN disclosed
US-11760724-B2 Pyridone compound production method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-19 US disclosed
CN-113200985-B Pteridinone compound and preparation method and application thereof 南开大学 2022-09-09 CN disclosed
EP-0061741-B1 TETRAHYDROPHTHALIMIDES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-18 EP disclosed
EP-0142769-A2 Tetrahydrobenzotriazoles, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-29 EP disclosed
US-4484941-A Tetrahydrophthalimides, and their production and use as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-27 US disclosed
US-4484940-A Tetrahydrophthalimides, and their production and use as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-27 US disclosed
EP-0105721-A2 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-indazoles, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-18 EP disclosed
US-4431822-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-02-14 US disclosed
EP-0083055-A2 Tetrahydrophthalimide compounds, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-06 EP disclosed
EP-0061741-A2 Tetrahydrophthalimides, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760724-B2 Pyridone compound production method C5, PNPO, PDXK HSD17B10 118/4885TSHR 706/4885HPGD 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.