Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8264405 | 0.98 | ALDH1A1 (0.47) | ALDH1A1S1PR4S1PR3CNR1EP300 | |
| SCHEMBL8264020 | 0.88 | F10 (0.43) | ALDH1A1S1PR4S1PR3EP300F10 | |
| SCHEMBL8265537 | 0.88 | ALDH1A1 (0.46) | ALDH1A1S1PR4S1PR3CNR1EP300 | |
| SCHEMBL8264515 | 0.86 | F10 (0.45) | F10F7MAPT | |
| SCHEMBL8264058 | 0.86 | MAPT (0.45) | ALDH1A1CNR1F10SMN1; SMN2MAPT | |
| SCHEMBL13439351 | 0.84 | F10 (0.44) | ALDH1A1CNR1F10SMN1; SMN2MAPT | |
| SCHEMBL8265403 | 0.84 | F10 (0.42) | ALDH1A1CNR1EP300F10SMN1; SMN2 | |
| SCHEMBL8262956 | 0.84 | MAPT (0.43) | ALDH1A1CNR1F10SMN1; SMN2HTT | |
| SCHEMBL8264054 | 0.84 | F10 (0.42) | ALDH1A1CNR1F10SMN1; SMN2FPR2 | |
| SCHEMBL8264410 | 0.83 | F10 (0.42) | ALDH1A1CNR1F10SMN1; SMN2FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678913-B2 | Ureas as factor Xa inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-7678913-B2 | Ureas as factor Xa inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |