Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509046 | 0.85 | MAOA (0.54) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL30549059 | 0.85 | MAOA (0.54) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL3785823 | 0.80 | MAOA (0.48) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL29706653 | 0.79 | MAOA (0.52) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL28475655 | 0.78 | MAOA (0.47) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL25270075 | 0.78 | MAOA (0.50) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL12480139 | 0.77 | MAOA (0.45) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL14320619 | 0.75 | MAOA (0.58) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL13827224 | 0.74 | MAOA (0.47) | MAOACYP3A4CASP1RECQLMAP4K4 | |
| SCHEMBL28625348 | 0.74 | MAOA (0.47) | MAOACYP3A4CASP1RECQLMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177518-A1 | Organic compounds | Novartis AG (CH) | 2010-04-21 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |