Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746621 | 0.86 | KMT2A (0.60) | KMT2AMEN1L3MBTL1GRM1GSTO1 | |
| SCHEMBL1747338 | 0.82 | KMT2A (0.56) | KMT2AMEN1L3MBTL1GRM1GSTO1 | |
| SCHEMBL1747124 | 0.82 | KMT2A (0.58) | KMT2AMEN1L3MBTL1GRM1GSTO1 | |
| SCHEMBL18674659 | 0.82 | KMT2A (0.53) | KMT2AMEN1L3MBTL1GRM1GSTO1 | |
| SCHEMBL18674605 | 0.81 | GSTO1 (0.62) | KMT2AMEN1L3MBTL1GRM1GSTO1 | |
| SCHEMBL18674599 | 0.81 | KMT2A (0.64) | KMT2AMEN1L3MBTL1GRM1GSTO1 | |
| SCHEMBL20243713 | 0.80 | GCGR (0.65) | — | |
| SCHEMBL1746662 | 0.80 | KMT2A (0.57) | KMT2AMEN1L3MBTL1GRM1GSTO1 | |
| SCHEMBL1745036 | 0.77 | MEN1 (0.53) | KMT2AMEN1L3MBTL1GSTO1NPC1 | |
| SCHEMBL1746506 | 0.77 | KMT2A (0.57) | KMT2AMEN1L3MBTL1GRM1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074262-A1 | UBIQUITIN LIGASE INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |