Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5177298 | 0.97 | F10 (0.45) | POLBUSP2F10F2KMT2A | |
| SCHEMBL8266805 | 0.85 | ALDH1A1 (0.48) | F10F2HTTALDH1A1PLAU | |
| Acetic Acid SCHEMBL5176437 | 0.82 | CYP1A2 (0.47) | F10F2HTTALDH1A1PLAU | |
| Acetic Acid SCHEMBL5089036 | 0.79 | F10 (0.46) | USP2F10F2ALDH1A1PLAU | |
| SCHEMBL8265544 | 0.79 | F10 (0.43) | F10F2ALDH1A1PLAUKLKB1 | |
| SCHEMBL5188933 | 0.79 | F10 (0.44) | USP2F10F2ALDH1A1PLAU | |
| SCHEMBL8264943 | 0.79 | F10 (0.54) | F10F2HTTALDH1A1PLAU | |
| SCHEMBL8266386 | 0.78 | F10 (0.45) | POLBF10F2PLAUNPC1 | |
| SCHEMBL8267078 | 0.78 | F10 (0.44) | F10F2PLAUKLKB1MAPT | |
| Hydrochloric Acid SCHEMBL5088330 | 0.78 | F10 (0.45) | USP2F10F2ALDH1A1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027135-A1 | 4-AMINOMETHYL BENZAMIDINE DERIVATIVES AND THEIR USE AS FACTOR VIIIA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-16 | — | — | WO | disclosed |