Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8267959 | 0.92 | HPGD (0.49) | HPGDPTK2BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2035230 | 0.91 | ADK (0.49) | HPGDPTK2BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8157178 | 0.86 | ADK (0.59) | HPGDKDM4EADKMEN1ALDH1A1 | |
| SCHEMBL8215375 | 0.86 | ADK (0.42) | HPGDPTK2BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2035057 | 0.86 | ADK (0.48) | HPGDKDM4EADKMEN1ALDH1A1 | |
| SCHEMBL8254635 | 0.85 | ADK (0.42) | HPGDKDM4EADKMEN1ALDH1A1 | |
| SCHEMBL8147922 | 0.85 | ADK (0.45) | HPGDKDM4EADKMEN1ALDH1A1 | |
| SCHEMBL8248619 | 0.83 | ADK (0.42) | HPGDKDM4EADKMEN1ALDH1A1 | |
| SCHEMBL2042392 | 0.83 | ADK (0.44) | HPGDKDM4EPPARGNR2E3NCOR2 | |
| SCHEMBL8265827 | 0.83 | HPGD (0.52) | HPGDPTK2BCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |