Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 12/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 12/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 12/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.44 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796541 | 0.89 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1CA2CHKA | |
| SCHEMBL951611 | 0.89 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1CA2CHKA | |
| SCHEMBL7425278 | 0.89 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1CA2CHKA | |
| SCHEMBL24855882 | 0.87 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1CA2CHKA | |
| Hydrochloric Acid SCHEMBL7419974 | 0.87 | TPSAB1 (0.57) | TPSAB1TPSD1TPSG1CA2CHKA | |
| SCHEMBL30743824 | 0.87 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1CA2CHKA | |
| Hydrochloric Acid SCHEMBL8188321 | 0.87 | TPSAB1 (0.57) | TPSAB1TPSD1TPSG1CA2CHKA | |
| SCHEMBL17479229 | 0.87 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1CA2CHKA | |
| SCHEMBL26929377 | 0.86 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1CA2CHKA | |
| SCHEMBL28067576 | 0.85 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006004880-A2 | SUBSTITUTED N-ARYLSULFONYLHETEROCYCLIC AMINES AS GAMMA-SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2006-01-12 | — | — | WO | disclosed |