Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.69 |
| ▸ | ITGAV | P06756 | 13/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14356378 | 0.92 | ITGB3 (0.83) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356369 | 0.90 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356360 | 0.88 | ITGB3 (0.84) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356377 | 0.84 | ITGB3 (0.84) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356356 | 0.83 | ITGB3 (0.89) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356372 | 0.83 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356368 | 0.82 | ITGB3 (0.89) | ITGB3ITGAVITGA2B | |
| SCHEMBL14356358 | 0.78 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL2419825 | 0.78 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL14387729 | 0.77 | ITGB3 (0.84) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006015382-A2 | INTEGRIN ALPHA-V BETA-3 ANTAGONISTS FOR USE IN IMAGING AND THERAPY | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) | 2006-02-09 | — | — | WO | disclosed |