Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 2/20 | 0.32 |
| ▸ | PDE1A | P54750 | 3/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602702 | 0.87 | PDE1C (0.36) | MERTKPDE1APDE1BPDE1C | |
| SCHEMBL5346457 | 0.87 | PDE1C (0.33) | MERTKPDE1APDE1BPDE1C | |
| SCHEMBL3602836 | 0.87 | MERTK (0.33) | MERTKPDE1APDE1BPDE1C | |
| SCHEMBL5452107 | 0.87 | MERTK (0.40) | MERTKPDE1APDE1BPDE1C | |
| SCHEMBL3607708 | 0.87 | KHK (0.37) | MERTKPDE1APDE1BPDE1C | |
| SCHEMBL3609189 | 0.87 | PDE1C (0.39) | PDE1APDE1BPDE1C | |
| SCHEMBL3594040 | 0.86 | PTGS2 (0.42) | MERTKPDE1APDE1BPDE1C | |
| SCHEMBL3593433 | 0.86 | PDE1C (0.35) | MERTKPDE1APDE1BPDE1C | |
| SCHEMBL3607885 | 0.86 | PDE1C (0.45) | PDE1APDE1BPDE1C | |
| SCHEMBL5459121 | 0.85 | KHK (0.41) | MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006044528-A1 | PYRAZOLE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-04-27 | — | — | WO | disclosed |