Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985990 | 0.87 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4821574 | 0.87 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14189763 | 0.82 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4816968 | 0.82 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL4816976 | 0.82 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL4827006 | 0.81 | ALDH1A1 (0.53) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL4818719 | 0.76 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL4818725 | 0.76 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DNQO2 | |
| SCHEMBL4819741 | 0.75 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL4819738 | 0.75 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006026747-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |