Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945342 | 0.96 | DPP4 (0.48) | DPP4CHRM1ALDH1A1LMNATSHR | |
| SCHEMBL13944307 | 0.94 | DPP4 (0.48) | DPP4CHRM1ALDH1A1LMNATSHR | |
| SCHEMBL8271382 | 0.94 | DPP4 (0.52) | DPP4CHRM1ALDH1A1LMNATSHR | |
| SCHEMBL8271381 | 0.92 | DPP4 (0.51) | DPP4CHRM1 | |
| SCHEMBL13923916 | 0.92 | DPP4 (0.60) | DPP4CHRM1 | |
| SCHEMBL13944761 | 0.90 | DPP4 (0.48) | DPP4CHRM1 | |
| SCHEMBL8270425 | 0.88 | DPP4 (0.59) | DPP4CHRM1 | |
| SCHEMBL13944303 | 0.87 | ALDH1A1 (0.49) | DPP4CHRM1ALDH1A1LMNATSHR | |
| SCHEMBL8270632 | 0.86 | DPP4 (0.51) | DPP4CHRM1ALDH1A1LMNATSHR | |
| SCHEMBL13923861 | 0.86 | DPP4 (0.64) | DPP4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027204-A1 | 8-(3-AMINO-PIPERIDIN-1-YL)-7-(BUT-2-INYL)-XANTHINES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-03-16 | — | — | WO | disclosed |