Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827864 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2720720 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6294312 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL18152940 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL292448 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL3355394 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL1776903 | 0.67 | — | — | |
| SCHEMBL819339 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL1115876 | 0.66 | BCHE (0.37) | — | |
| Hydrochloric Acid SCHEMBL6478743 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445921-B1 | NANO-LINKED HETERONUCLEAR METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2017-02-22 | — | — | EP | disclosed |
| US-8143430-B2 | Nano-linked heteronuclear metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110144290-A1 | NANO-LINKED HETERONUCLEAR METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-06-16 | — | — | US | disclosed |
| US-7919639-B2 | Nano-linked heteronuclear metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100324236-A1 | NANO-LINKED HETERONUCLEAR METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-12-23 | — | — | US | disclosed |