Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13288525 | 0.89 | HDAC2 (0.56) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL13288496 | 0.83 | HDAC2 (0.59) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL8271626 | 0.79 | HDAC2 (0.54) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL8270647 | 0.79 | HDAC2 (0.57) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL13288526 | 0.77 | HDAC2 (0.52) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL13288519 | 0.75 | HDAC1 (0.64) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL27659688 | 0.73 | CNR1 (0.48) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL8270611 | 0.73 | HDAC2 (0.60) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL13288534 | 0.72 | HDAC1 (0.63) | HDAC1HDAC2HDAC6HDAC11HDAC8 | |
| SCHEMBL8271583 | 0.72 | HDAC2 (0.68) | HDAC1HDAC2HDAC6HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006017216-A1 | HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2006-02-16 | — | — | WO | disclosed |