Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13288526 | 0.93 | HDAC2 (0.52) | CNR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL13288496 | 0.79 | HDAC2 (0.59) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL27679543 | 0.78 | HDAC8 (0.61) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL13288525 | 0.78 | HDAC2 (0.56) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL8270647 | 0.74 | HDAC2 (0.57) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL7278495 | 0.74 | PLAAT3 (0.74) | PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8270626 | 0.73 | HDAC1 (0.52) | CNR1HDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL7280544 | 0.73 | ALDH1A1 (0.62) | PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27659497 | 0.73 | HDAC8 (0.57) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL10436226 | 0.73 | PLAAT3 (0.73) | PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997627-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | claimed |
| CN-1997627-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | disclosed |