Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269402 | 0.97 | CTSK (0.34) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL8269404 | 0.96 | CTSK (0.34) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL5804674 | 0.94 | CTSK (0.35) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL5791557 | 0.90 | CTSK (0.36) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL5794916 | 0.89 | CTSK (0.35) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL8268876 | 0.89 | CTSK (0.34) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL5792642 | 0.89 | CTSK (0.36) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL8269413 | 0.88 | FGFR4 (0.36) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL8270723 | 0.88 | CTSK (0.39) | CTSKCTSLCTSBCTSSFGFR4 | |
| SCHEMBL8270026 | 0.87 | FGFR4 (0.36) | CTSKCTSLCTSBCTSSFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |