Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
| ▸ | ITGAL | P20701 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14162983 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HTTGRM3GAASMN1; SMN2 | |
| SCHEMBL8271062 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1HTTJAK3JAK1GAA | |
| SCHEMBL5121118 | 0.79 | ALDH1A1 (0.42) | ALDH1A1JAK3GRM3JAK1MAPK1 | |
| SCHEMBL17928596 | 0.79 | HPGD (0.58) | ALDH1A1JAK3JAK1GAASMN1; SMN2 | |
| SCHEMBL18616042 | 0.79 | ALDH1A1 (0.42) | ALDH1A1JAK3GRM3JAK1MAPK1 | |
| SCHEMBL25366205 | 0.79 | HPGD (0.58) | ALDH1A1JAK3JAK1GAASMN1; SMN2 | |
| SCHEMBL18331786 | 0.79 | HPGD (0.58) | ALDH1A1JAK3JAK1GAASMN1; SMN2 | |
| SCHEMBL2251284 | 0.79 | ALDH1A1 (0.42) | ALDH1A1JAK3GRM3JAK1MAPK1 | |
| SCHEMBL1687961 | 0.79 | HPGD (0.58) | ALDH1A1JAK3JAK1GAASMN1; SMN2 | |
| SCHEMBL20839691 | 0.79 | JAK3 (0.46) | ALDH1A1HTTJAK3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012504-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | DAIAMED, INC. (US) | 2006-02-02 | — | — | WO | disclosed |