Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816195 | 0.92 | NPC1 (0.47) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL82386 | 0.92 | NPC1 (0.47) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL83801 | 0.85 | KDM4E (0.43) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL83781 | 0.83 | NPC1 (0.43) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL82329 | 0.82 | NPC1 (0.44) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL82989 | 0.79 | TAAR1 (0.41) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5780155 | 0.79 | PTGES (0.37) | HCRTR1HCRTR2GRIN2BLMNANPSR1 | |
| SCHEMBL29605577 | 0.78 | MAPT (0.38) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL394140 | 0.78 | MAPT (0.38) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6980670 | 0.78 | NPC1 (0.66) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8128943-B2 | Use of oxazole derivatives for controlling fish parasites | NOVARTIS AG (CH) | 2012-03-06 | — | — | US | claimed |
| US-20100303865-A1 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | claimed |
| EP-1931204-A1 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES | Novartis AG (CH) | 2008-06-18 | — | — | EP | claimed |
| WO-2007025694-A1 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES | NOVARTIS AG (CH) | 2007-03-08 | — | — | WO | claimed |
| US-8128943-B2 | Use of oxazole derivatives for controlling fish parasites | NOVARTIS AG (CH) | 2012-03-06 | — | — | US | disclosed |
| US-20100303865-A1 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | disclosed |
| EP-1931204-A1 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES | Novartis AG (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007025694-A1 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES | NOVARTIS AG (CH) | 2007-03-08 | — | — | WO | disclosed |
| US-20020137781-A1 | Preparation and use of enantiomer-pure 2,4-disubstituted oxazolines | FROELICH OLIVIER (FR) | 2002-09-26 | — | — | US | disclosed |
| EP-1165527-A1 | PESTICIDAL ENANTIOMER-PURE 2,4-DISUBSTITUTED OXAZOLINES | Novartis AG (CH) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058291-A1 | PESTICIDAL ENANTIOMER-PURE 2,4-DISUBSTITUTED OXAZOLINES | NOVARTIS AG (CH) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303865-A1 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES | OXA1L, NPY5R, ZFX | ALDH1A1 2870/4885MAPT 4207/4885NPC1 3540/4885 |
| US-20020137781-A1 | Preparation and use of enantiomer-pure 2,4-disubstituted oxazolines | CYP1B1, CYP2S1, CHRM1 | ALDH1A1 382/4885MAPT 4511/4885NPC1 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.