Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | GJB2 | P29033 | 2/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16127013 | 0.87 | CA12 (0.40) | ALDH1A1POLBGAA | |
| SCHEMBL10181805 | 0.87 | ALDH1A1 (0.40) | ALDH1A1BCHE | |
| SCHEMBL12203016 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1GJB2PPP5C | |
| SCHEMBL14885826 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1GJB2PPP5C | |
| SCHEMBL12157635 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1GJB2PPP5C | |
| SCHEMBL14236382 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1GJB2PPP5C | |
| SCHEMBL15747287 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1GJB2PPP5C | |
| SCHEMBL18483303 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1GJB2PPP5C | |
| SCHEMBL10182606 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TDP1BCHE | |
| SCHEMBL10039960 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1GJB2PPP5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006017180-A2 | GLYCOPEPTIDE DIMERS AND USES THEREOF | PROGENICS PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | WO | disclosed |