Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.54 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14281193 | 0.93 | F10 (0.53) | F10MEN1LMNAMAPTMAPK1 | |
| SCHEMBL4923283 | 0.83 | F10 (0.51) | F10MEN1LMNAMAPTMAPK1 | |
| SCHEMBL8272697 | 0.82 | F10 (0.57) | F10 | |
| SCHEMBL8273683 | 0.80 | F10 (0.51) | F10 | |
| SCHEMBL8272008 | 0.80 | F10 (0.51) | F10 | |
| SCHEMBL14281196 | 0.79 | F10 (0.52) | F10 | |
| SCHEMBL4476981 | 0.79 | F10 (0.67) | F10MEN1LMNAMAPTMAPK1 | |
| SCHEMBL8274770 | 0.78 | F10 (0.49) | F10 | |
| SCHEMBL8273620 | 0.78 | F10 (0.49) | F10 | |
| SCHEMBL8272899 | 0.78 | F10 (0.54) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121103-A1 | BENZIMIDAZOLES, METHOD FOR PRODUCING THEM AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-22 | — | — | WO | disclosed |