SCHEMBL8272008

SCHEMBL8272008

CCCC(C(=O)Nc1ccc(N2CCOCC2=O)c(Cl)c1)c1nc2ccc(Cl)cc2[nH]1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14281196 0.93 F10 (0.52) F10
SCHEMBL8272899 0.92 F10 (0.54) F10
SCHEMBL8273620 0.92 F10 (0.49) F10
SCHEMBL8274770 0.92 F10 (0.49) F10
SCHEMBL8272015 0.89 MAPT (0.48)
SCHEMBL8273619 0.87 F10 (0.45) F10
SCHEMBL14281195 0.81 F10 (0.45) F10
SCHEMBL14281186 0.81 F10 (0.55) F10
SCHEMBL8272007 0.80 F10 (0.54) F10
SCHEMBL4921727 0.77 F10 (0.49) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005121103-A1 BENZIMIDAZOLES, METHOD FOR PRODUCING THEM AND THE USE THEREOF AS DRUGS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-12-22 WO disclosed