Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 19/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 19/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 19/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 18/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 18/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 18/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 18/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 18/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 18/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998516 | 0.88 | HDAC1 (0.84) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL8272475 | 0.82 | HDAC1 (0.69) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL5998899 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL5999560 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL8587363 | 0.78 | HDAC1 (0.75) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL5240357 | 0.78 | HDAC6 (0.78) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL8226957 | 0.77 | HDAC1 (1.00) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL38652239 | 0.76 | HDAC1 (0.62) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL8294749 | 0.76 | HDAC1 (0.44) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL8228208 | 0.76 | HDAC1 (0.86) | HDAC1HDAC3HDAC8HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028972-A2 | MERCAPTOAMIDES AS HISTONE DEACETYLASE INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2006-03-16 | — | — | WO | disclosed |