SCHEMBL8273201

SCHEMBL8273201

CC#CCn1c(N(C)CC(C)(C)N)nc2c1c(=O)n(Cc1ncccc1N)c(=O)n2C

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 19/20 0.44
DPP9 Q86TI2 1/20 0.40
CHRM1 P11229 1/20 0.38
FAP Q12884 3/20 0.38
HTT P42858 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4464092 0.90 DPP4 (0.46) DPP4DPP9CHRM1
SCHEMBL8273204 0.88 DPP4 (0.45) DPP4DPP9CHRM1FAPHTT
SCHEMBL8273195 0.87 DPP4 (0.45) DPP4DPP9FAP
SCHEMBL8272012 0.87 DPP4 (0.44) DPP4DPP9CHRM1FAPHTT
SCHEMBL8273199 0.86 DPP4 (0.49) DPP4DPP9CHRM1FAP
SCHEMBL8273219 0.85 DPP4 (0.45) DPP4DPP9CHRM1FAP
SCHEMBL8273228 0.85 DPP4 (0.48) DPP4DPP9CHRM1FAPHTT
SCHEMBL8271561 0.85 DPP4 (0.46) DPP4DPP9CHRM1FAPHTT
SCHEMBL8272023 0.84 DPP4 (0.46) DPP4DPP9CHRM1FAP
SCHEMBL8272357 0.83 DPP4 (0.41) DPP4DPP9CHRM1FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006029769-A1 NOVEL 3-METHYL-7-BUTINYL-XANTHINES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-03-23 WO disclosed