Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251584 | 0.87 | PKM (0.42) | PKMMAPK1HCRTR1HCRTR2PTGER1 | |
| SCHEMBL3246173 | 0.84 | PKM (0.46) | PKMHCRTR1HCRTR2HIF1AEPAS1 | |
| SCHEMBL3255615 | 0.83 | PKM (0.43) | PKMHCRTR1HCRTR2HIF1AEPAS1 | |
| SCHEMBL3244577 | 0.83 | PKM (0.42) | PKMMAPK1HCRTR1HCRTR2PTGER1 | |
| SCHEMBL3249119 | 0.81 | PKM (0.41) | PKMMAPK1HCRTR1HCRTR2PTGER1 | |
| SCHEMBL3246519 | 0.81 | PKM (0.41) | PKMMAPK1HCRTR1HCRTR2PTGER1 | |
| SCHEMBL3256185 | 0.80 | PKM (0.40) | PKMMAPK1HCRTR1HCRTR2PTGER1 | |
| SCHEMBL3247753 | 0.80 | PKM (0.57) | PKMMAPK1HCRTR1HCRTR2PTGER1 | |
| SCHEMBL3253757 | 0.79 | MAPK1 (0.48) | PKMMAPK1HCRTR1HCRTR2PTGER1 | |
| SCHEMBL3251293 | 0.79 | PKM (0.42) | PKMMAPK1HCRTR1HCRTR2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024779-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI-AVENTIS (FR) | 2006-03-09 | — | — | WO | disclosed |