Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925760 | 0.93 | EPHX2 (0.44) | MOKEPHX2HRH3AKT1GPR35 | |
| SCHEMBL14281189 | 0.87 | DPP4 (0.42) | HRH4HRH3SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4916310 | 0.85 | HRH4 (0.42) | HRH4HRH3ALDH1A1NPC1MAPT | |
| SCHEMBL8272905 | 0.83 | MLLT1 (0.48) | HRH4HRH3ALDH1A1HPGDHTT | |
| SCHEMBL8273650 | 0.82 | HRH4 (0.43) | HRH4HRH3SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL14281186 | 0.81 | F10 (0.55) | — | |
| SCHEMBL4915184 | 0.80 | CCKBR (0.38) | HRH4HRH3AKT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8272693 | 0.80 | HRH4 (0.43) | HRH4HRH3ALDH1A1MAPTHPGD | |
| SCHEMBL8274765 | 0.79 | HRH4 (0.42) | HRH4HRH3SMN1; SMN2HPGDALOX15 | |
| SCHEMBL8274771 | 0.78 | HRH4 (0.43) | HRH4HRH3ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | GERLACH KAI | 2008-01-17 | — | — | US | disclosed |
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | GERLACH KAI | 2008-01-17 | — | — | US | disclosed |
| WO-2005121103-A1 | BENZIMIDAZOLES, METHOD FOR PRODUCING THEM AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | CYP2C19, CYP3A4, CYP2B6 | MOK 2871/4885EPHX2 3826/4885HRH4 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.