SCHEMBL8273658

SCHEMBL8273658

CCC(C)[C@@H]1NC[C@@H](C)Oc2ccccc2CCCNC(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)CN(C)C1=O

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8273504 0.94 GHSR (0.83) GHSR
SCHEMBL8273659 0.93 GHSR (0.84) GHSR
SCHEMBL805018 0.91 GHSR (0.89) GHSR
SCHEMBL2758810 0.89 GHSR (0.81) GHSR
SCHEMBL8273505 0.87 GHSR (0.82) GHSR
SCHEMBL8274225 0.85 GHSR (0.72) GHSR
SCHEMBL804937 0.85 GHSR (1.00) GHSR
SCHEMBL14011144 0.85 GHSR (1.00) GHSR
SCHEMBL12657975 0.85 GHSR (1.00) GHSR
SCHEMBL13788301 0.85 GHSR (0.90) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006009645-A1 METHODS OF USING MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR TRANZYME PHARMA, INC. (US) 2006-01-26 WO disclosed