Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 20/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8272433 | 0.93 | GHSR (0.70) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8273657 | 0.90 | GHSR (0.66) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11983042 | 0.90 | GHSR (1.00) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14311427 | 0.90 | GHSR (1.00) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL804934 | 0.90 | GHSR (1.00) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8273659 | 0.89 | GHSR (0.84) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8273505 | 0.89 | GHSR (0.82) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8274282 | 0.89 | GHSR (0.64) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13627184 | 0.86 | GHSR (0.82) | GHSRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8273593 | 0.85 | GHSR (0.60) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006009645-A1 | METHODS OF USING MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR | TRANZYME PHARMA, INC. (US) | 2006-01-26 | — | — | WO | disclosed |