Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494381 | 1.00 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTSCN5A | |
| SCHEMBL8222034 | 0.90 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTSCN5A | |
| SCHEMBL8276118 | 0.90 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTSCN5A | |
| SCHEMBL8274407 | 0.90 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTSCN5A | |
| SCHEMBL13544350 | 0.88 | ADAM17 (0.47) | ADAM17MEN1KMT2ANAMPT | |
| SCHEMBL8222661 | 0.88 | ADAM17 (0.53) | ADAM17MEN1KMT2ASCN5ASCN9A | |
| SCHEMBL8221017 | 0.88 | ADAM17 (0.42) | ADAM17MEN1KMT2ANAMPTDPP8 | |
| SCHEMBL8275183 | 0.88 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTSCN5A | |
| SCHEMBL8213656 | 0.86 | ADAM17 (0.54) | ADAM17MEN1KMT2ANAMPTSCN5A | |
| SCHEMBL8221487 | 0.85 | ADAM17 (0.40) | ADAM17MEN1KMT2ANAMPTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |