Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 7/20 | 1.00 |
| ▸ | AKT1 | P31749 | 2/20 | 1.00 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.58 |
| ▸ | ILK | Q13418 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 2/20 | 0.51 |
| ▸ | HIPK1 | Q86Z02 | 2/20 | 0.51 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.51 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28198087 | 1.00 | AKT2 (1.00) | AKT2AKT1ROCK2ILKCHEK1 | |
| Hydrochloric Acid SCHEMBL72435 | 0.98 | AKT2 (0.95) | AKT2AKT1ROCK2ILKCHEK1 | |
| SCHEMBL16872766 | 0.98 | AKT2 (0.95) | AKT2AKT1ROCK2ILKCHEK1 | |
| SCHEMBL15606681 | 0.93 | AKT2 (0.87) | AKT2AKT1ROCK2ILKCHEK1 | |
| SCHEMBL28941664 | 0.93 | AKT2 (0.87) | AKT2AKT1ROCK2ILKCHEK1 | |
| Phenol SCHEMBL27544955 | 0.89 | AKT2 (0.80) | AKT2AKT1ROCK2ILKCHEK1 | |
| SCHEMBL15689115 | 0.87 | AKT2 (0.76) | AKT2AKT1ROCK2ILKPIM1 | |
| SCHEMBL16432987 | 0.87 | AKT2 (0.76) | AKT2AKT1ROCK2ILKPIM1 | |
| SCHEMBL28552255 | 0.84 | AKT2 (0.72) | AKT2AKT1ROCK2ILKCHEK1 | |
| SCHEMBL3740850 | 0.84 | AKT2 (0.70) | AKT2AKT1ROCK2ILKCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118185037-A | Cu metal organic framework material, preparation method and ammonia adsorption application | 北京工业大学 | 2024-06-14 | — | — | CN | claimed |
| CN-117865422-B | Treatment process and system for softening high-salt negative hard wastewater and volatile organic compounds | 杭州水处理技术研究开发中心有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-115368249-B | Synthesis method of acryloyloxyethyl trimethyl ammonium chloride | 浙江鑫甬生物化工股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117865422-A | Treatment process and system for softening high-salt negative hard wastewater and volatile organic compounds | 杭州水处理技术研究开发中心有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-114933539-B | Synthesis method of methacryloyloxyethyl trimethyl ammonium chloride | 浙江鑫甬生物化工股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117065519-A | Method for capturing carbon dioxide by using ionic liquid composite absorbent | 浙江天地环保科技股份有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-116139936-B | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-07-04 | — | — | CN | claimed |
| CN-116139936-A | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-05-23 | — | — | CN | claimed |
| CN-113929919-B | Ni and Ba bimetal MOFs, preparation method and application | 西安近代化学研究所 | 2022-12-13 | — | — | CN | claimed |
| CN-115368249-A | Synthesis method of acryloyloxyethyltrimethyl ammonium chloride | 浙江鑫甬生物化工股份有限公司 | 2022-11-22 | — | — | CN | claimed |
| WO-2005051917-A9 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA SA (FR) | 2005-09-29 | — | — | WO | claimed |
| US-20050165005-A1 | Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2005-07-28 | — | — | US | claimed |
| WO-2005051917-A1 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA S.A. (FR) | 2005-06-09 | — | — | WO | claimed |
| EP-1435957-A4 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3BETA PROTEIN AND PROTEIN COMPLEXES | VERTEX PHARMA (US) | 2005-04-13 | — | — | EP | claimed |
| EP-1435957-A2 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3BETA PROTEIN AND PROTEIN COMPLEXES | Vertex Pharmaceuticals Incorporated (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2002088078-A2 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3β PROTEIN AND PROTEIN COMPLEXES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2002-11-07 | — | — | WO | claimed |
| US-5840913-A | CATALYTIC N-ALKYLATION OF A PYRAZOLE BY REACTING WITH AN ALCOHOL; LIQUID PHASE; NON-HETEROGENOUS ACID CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | claimed |
| US-5468871-A | Catalytic N-alkylation | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
| US-4321395-A | Preparation of acetanilides | BASF AKTIENGESELLSCHAFT (DE) | 1982-03-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165005-A1 | Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them | C1R, CBR3, C3AR1 | AKT2 968/4885AKT1 1696/4885ROCK2 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.