SCHEMBL28552255

SCHEMBL28552255

c1ccc(-c2ccccc2-c2cn[nH]c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT2 P31751 4/20 0.72
AKT1 P31749 2/20 0.72
CLK2 P49760 2/20 0.50
HIPK1 Q86Z02 2/20 0.50
HIPK2 Q9H2X6 2/20 0.50
HIPK3 Q9H422 2/20 0.50
CLK4 Q9HAZ1 2/20 0.50
DYRK2 Q92630 1/20 0.50
FYN P06241 1/20 0.50
FEN1 P39748 2/20 0.49
CLK1 P49759 1/20 0.48
PDK2 Q15119 1/20 0.46
ROCK2 O75116 1/20 0.45
METAP2 P50579 1/20 0.44
CHEK1 O14757 2/20 0.44
PIM1 P11309 1/20 0.44
CHEK2 O96017 1/20 0.44
LMNA P02545 1/20 0.44
ILK Q13418 1/20 0.43
ADRA1D P25100 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30823569 0.87 AKT2 (0.59) AKT2AKT1CLK2HIPK1HIPK2
SCHEMBL30823568 0.87 AKT2 (0.59) AKT2AKT1CLK2HIPK1HIPK2
SCHEMBL20294499 0.87 AKT2 (0.60) AKT2AKT1CLK2HIPK1HIPK2
SCHEMBL31482437 0.85 AKT2 (0.63) AKT2AKT1CLK2HIPK1HIPK2
SCHEMBL82741 0.84 AKT2 (1.00) AKT2AKT1CLK2HIPK1HIPK2
Benzene SCHEMBL28198087 0.84 AKT2 (1.00) AKT2AKT1CLK2HIPK1HIPK2
SCHEMBL28731887 0.82 ROCK2 (0.50) AKT2AKT1ROCK2
SCHEMBL16872766 0.82 AKT2 (0.95) AKT2AKT1CLK2HIPK1HIPK2
Hydrochloric Acid SCHEMBL72435 0.82 AKT2 (0.95) AKT2AKT1CLK2HIPK1HIPK2
SCHEMBL21142334 0.81 AKT2 (0.53) AKT2AKT1CLK2HIPK1HIPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113941364-B Pb and Ba bimetallic MOFs, preparation method and application 西安近代化学研究所 2024-03-22 CN claimed
CN-114314584-A Preparation method and application of performance-repeatable porous multi-polarization nano carbon material 盐城工学院 2022-04-12 CN claimed
CN-112500582-B Multinuclear cobalt cluster metal organic framework material based on four-head pyrazole ligand, preparation and application 北京工业大学 2022-03-29 CN claimed
CN-113941364-A Pb and Ba bimetal MOFs, preparation method and application 西安近代化学研究所 2022-01-18 CN claimed
CN-113620878-A Ni metal-organic framework material and preparation method and application thereof 山西大学 2021-11-09 CN claimed
CN-112500582-A Multinuclear cobalt cluster metal organic framework material based on four-head pyrazole ligand, preparation and application 北京工业大学 2021-03-16 CN claimed
CN-113941364-B Pb and Ba bimetallic MOFs, preparation method and application 西安近代化学研究所 2024-03-22 CN disclosed
CN-113941364-B Pb and Ba bimetallic MOFs, preparation method and application 西安近代化学研究所 2024-03-22 CN disclosed
CN-114314584-B Preparation method and application of performance-repeatable pore multi-polarization nano carbon material 盐城工学院 2023-12-12 CN disclosed
CN-114314584-A Preparation method and application of performance-repeatable porous multi-polarization nano carbon material 盐城工学院 2022-04-12 CN disclosed
CN-112500582-B Multinuclear cobalt cluster metal organic framework material based on four-head pyrazole ligand, preparation and application 北京工业大学 2022-03-29 CN disclosed
CN-112500582-B Multinuclear cobalt cluster metal organic framework material based on four-head pyrazole ligand, preparation and application 北京工业大学 2022-03-29 CN disclosed
CN-113941364-A Pb and Ba bimetal MOFs, preparation method and application 西安近代化学研究所 2022-01-18 CN disclosed
CN-113941364-A Pb and Ba bimetal MOFs, preparation method and application 西安近代化学研究所 2022-01-18 CN disclosed
CN-112500582-A Multinuclear cobalt cluster metal organic framework material based on four-head pyrazole ligand, preparation and application 北京工业大学 2021-03-16 CN disclosed
CN-112500582-A Multinuclear cobalt cluster metal organic framework material based on four-head pyrazole ligand, preparation and application 北京工业大学 2021-03-16 CN disclosed