Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 13/20 | 0.83 |
| ▸ | ACHE | P22303 | 4/20 | 0.72 |
| ▸ | DRD2 | P14416 | 2/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.65 |
| ▸ | DRD3 | P35462 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725669 | 0.91 | HTR4 (1.00) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL17709611 | 0.90 | HTR4 (0.79) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7035321 | 0.90 | HTR4 (0.98) | HTR4ACHEDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL726793 | 0.90 | HTR4 (0.98) | HTR4ACHEDRD2DRD4DRD3 | |
| SCHEMBL27886820 | 0.89 | HTR4 (0.68) | HTR4ACHEDRD2DRD4DRD3 | |
| SCHEMBL6583155 | 0.88 | HTR4 (0.76) | HTR4ACHE | |
| SCHEMBL14827422 | 0.86 | HTR4 (0.75) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL8234943 | 0.85 | HTR4 (0.66) | HTR4ACHEDRD2DRD4DRD3 | |
| SCHEMBL1501983 | 0.85 | HTR4 (0.68) | HTR4ACHEDRD2DRD4DRD3 | |
| SCHEMBL1501986 | 0.85 | HTR4 (0.68) | HTR4ACHEDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092882-A1 | 4-AMINO-5-HALOGENO-BENZAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL, CNS, NEUROLOGICAL AND CARDIOVASCULAR DISORDERS | PFIZER JAPAN, INC. (JP) | 2005-10-06 | — | — | WO | disclosed |