Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274902 | 0.88 | KDM4E (0.57) | KDM4EUSP2POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL8215109 | 0.78 | KDM4E (0.45) | KDM4EUSP2POLBL3MBTL1HTR1A | |
| SCHEMBL8273724 | 0.71 | ADAM17 (0.49) | KDM4EPOLBALDH1A1HTTKMT2A | |
| SCHEMBL13542436 | 0.70 | ADAM17 (0.46) | KDM4EPOLBL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8215093 | 0.70 | ADAM17 (0.48) | KDM4EL3MBTL1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8223831 | 0.70 | ADAM17 (0.48) | KDM4EPOLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6778574 | 0.70 | KDM4E (0.59) | KDM4EUSP2POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL6778571 | 0.70 | KDM4E (0.59) | KDM4EUSP2POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL8223839 | 0.69 | ADAM17 (0.51) | POLBALDH1A1HTTKMT2ALMNA | |
| SCHEMBL8275719 | 0.68 | HTT (0.60) | KDM4EPOLBSMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |