SCHEMBL8275239

SCHEMBL8275239

Cc1ccc2c(c1)CCC/C2=N\O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.53
HPGD P15428 1/20 0.53
HTT P42858 1/20 0.50
TSHR P16473 1/20 0.46
MAPT P10636 4/20 0.44
NPC1 O15118 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
RAB9A P51151 1/20 0.44
PARP10 Q53GL7 1/20 0.41
PARP11 Q9NR21 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PLA2G1B P04054 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
ALDH1A1 P00352 5/20 0.40
MAPK1 P28482 2/20 0.40
GAA P10253 2/20 0.40
ALOX12 P18054 2/20 0.40
LMNA P02545 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10041967 1.00 L3MBTL1 (0.53) L3MBTL1HPGDHTTTSHRMAPT
SCHEMBL23878719 1.00 L3MBTL1 (0.53) L3MBTL1HPGDHTTTSHRMAPT
SCHEMBL31303001 0.89 HTT (0.62) L3MBTL1HPGDHTTMAPTNPC1
SCHEMBL12609506 0.89 HTT (0.62) L3MBTL1HPGDHTTMAPTNPC1
SCHEMBL14468278 0.89 HTT (0.62) L3MBTL1HPGDHTTMAPTNPC1
SCHEMBL5466822 0.86 L3MBTL1 (0.53) L3MBTL1HPGDHTTTSHRMAPT
SCHEMBL30995675 0.86 L3MBTL1 (0.53) L3MBTL1HPGDHTTTSHRMAPT
SCHEMBL5272128 0.86 L3MBTL1 (0.53) L3MBTL1HPGDHTTTSHRMAPT
SCHEMBL25492569 0.84 PARP10 (0.42) L3MBTL1HPGDMAPTNPC1SMN1; SMN2
SCHEMBL5123714 0.83 PARP10 (0.50) L3MBTL1HPGDHTTTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12185626-B2 Chemical compounds, optoelectronic elements comprising at least one new chemical compound, and use of new chemical compounds in an optoelectronic element HELIATEK GMBH (DE) 2024-12-31 US disclosed
EP-3890041-B1 NEW CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT HELIATEK GMBH (DE) 2024-12-04 EP disclosed
US-20230165146-A1 CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT HELIATEK GMBH (DE) 2023-05-25 US disclosed
US-20230165146-A1 CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT HELIATEK GMBH (DE) 2023-05-25 US disclosed
US-20230165146-A1 CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT HELIATEK GMBH (DE) 2023-05-25 US disclosed
WO-2021198388-A1 NEW CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT HELIATEK GMBH (DE) 2021-10-07 WO disclosed
WO-2021198388-A1 NEW CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT HELIATEK GMBH (DE) 2021-10-07 WO disclosed
EP-3890041-A1 NEW CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT Heliatek GmbH (DE) 2021-10-06 EP disclosed
EP-3890041-A1 NEW CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT Heliatek GmbH (DE) 2021-10-06 EP disclosed
EP-2592071-B1 Tricyclic heterocyclic compounds BRISTOL MYERS SQUIBB CO (US) 2019-09-18 EP disclosed
EP-1758883-B1 Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors SCHERING CORP (US) 2011-11-02 EP disclosed
EP-2080752-A1 Pesticidally active ketone and oxime derivatives Syngenta Participations AG (CH) 2009-07-22 EP disclosed
WO-2005116009-A1 SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS SCHERING CORPORATION (US) 2005-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165146-A1 CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT ETV6, ALK, CHRM3 L3MBTL1 1636/4885HPGD 4655/4885HTT 2009/4885
US-12185626-B2 Chemical compounds, optoelectronic elements comprising at least one new chemical compound, and use of new chemical compounds in an optoelectronic element ETV6, ALK, CHRM3 L3MBTL1 1636/4885HPGD 4655/4885HTT 2009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.