Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12691906 | 0.74 | — | — | |
| SCHEMBL20573106 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL29138431 | 0.71 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL6356441 | 0.71 | SLC6A2 (0.35) | ALDH1A1 | |
| SCHEMBL29138432 | 0.70 | SLC6A2 (0.38) | ALDH1A1 | |
| SCHEMBL13881363 | 0.68 | GRIK1 (0.35) | ALDH1A1 | |
| SCHEMBL13783789 | 0.65 | MGAM (0.38) | ALDH1A1 | |
| SCHEMBL5642488 | 0.65 | SMN1; SMN2 (0.49) | ALDH1A1 | |
| SCHEMBL13060426 | 0.65 | GRIK1 (0.42) | — | |
| SCHEMBL5641654 | 0.64 | SMN1; SMN2 (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147608-A1 | Cyclopropyl beta-amino acid derivatives | SCHWARZ JACOB BRADLEY (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147608-A1 | Cyclopropyl beta-amino acid derivatives | CACNA1S, CACNA1D, CACNA1B | ALDH1A1 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.