Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223423 | 0.92 | NAMPT (0.42) | NAMPTDPP8DPP9 | |
| SCHEMBL12214264 | 0.81 | NAMPT (0.43) | NAMPTDPP8DPP9 | |
| SCHEMBL8221931 | 0.78 | NAMPT (0.41) | NAMPTDPP8DPP9 | |
| SCHEMBL8222522 | 0.76 | NAMPT (0.40) | NAMPTDPP8DPP9 | |
| SCHEMBL13542638 | 0.73 | NAMPT (0.41) | NAMPTDPP8DPP9 | |
| SCHEMBL8224584 | 0.71 | NAMPT (0.39) | NAMPTDPP8DPP9 | |
| SCHEMBL8418423 | 0.69 | DPP8 (0.42) | NAMPTDPP8DPP9 | |
| SCHEMBL8222517 | 0.68 | NAMPT (0.37) | NAMPTDPP8DPP9 | |
| SCHEMBL13542844 | 0.68 | NAMPT (0.44) | NAMPTDPP8DPP9 | |
| SCHEMBL8222058 | 0.67 | DPP8 (0.42) | NAMPTDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |