Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | CKS1B | P61024 | 5/20 | 0.37 |
| ▸ | SKP1 | P63208 | 5/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223154 | 0.82 | CHRM4 (0.46) | CHRM4ADAM17 | |
| SCHEMBL8222801 | 0.81 | CHRM4 (0.49) | CHRM4ADAM17 | |
| SCHEMBL8217041 | 0.79 | CHRM4 (0.47) | CHRM4ADAM17SSTR1SSTR4DRD2 | |
| SCHEMBL8222066 | 0.78 | CHRM4 (0.45) | CHRM4ADAM17DRD2 | |
| SCHEMBL8217133 | 0.76 | CHRM4 (0.49) | CHRM4ADAM17 | |
| SCHEMBL8222110 | 0.76 | CHRM4 (0.45) | CHRM4ADAM17CKS1BSKP1SKP2 | |
| SCHEMBL8221943 | 0.74 | CHRM4 (0.43) | CHRM4ADAM17 | |
| SCHEMBL8224737 | 0.74 | CHRM4 (0.41) | CHRM4ADAM17CKS1BSKP1SKP2 | |
| SCHEMBL8275503 | 0.74 | CHRM4 (0.43) | CHRM4ADAM17 | |
| SCHEMBL8221929 | 0.73 | CHRM4 (0.44) | CHRM4ADAM17SSTR1SSTR4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |