Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274031 | 1.00 | CTSB (0.53) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL13522781 | 0.94 | CTSB (0.55) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL8274106 | 0.94 | CTSB (0.55) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL8272992 | 0.94 | CTSB (0.55) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL10193686 | 0.94 | CTSB (0.54) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL693682 | 0.94 | CTSB (0.55) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL8273160 | 0.94 | CTSB (0.60) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL12676434 | 0.93 | CTSB (0.52) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL8273175 | 0.91 | CTSB (0.49) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL8273042 | 0.89 | CTSB (0.48) | CTSBPPP3CBABCC1ABCC2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006020276-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |