SCHEMBL8278

SCHEMBL8278

CC(C)(C)[Si](C)(C)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16047936 0.96
SCHEMBL5609364 0.96
Hydroxyamine SCHEMBL9902146 0.89
SCHEMBL1002050 0.85
SCHEMBL763573 0.85
Alcohol SCHEMBL1240463 0.84 ALDH1A1 (0.35)
Bromoethane SCHEMBL8559803 0.84 ALDH1A1 (0.35)
SCHEMBL15161790 0.79
Hydroquinone SCHEMBL4804304 0.78 ESR1 (0.44)
SCHEMBL9628862 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9857 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623993-B2 Synthesis of vinyl cyclobutyl intermediates AMGEN INC. (US) 2026-05-12 US claimed
CN-122025826-A Wide-temperature-range lithium battery electrolyte and preparation method thereof 安徽兴锂新能源有限公司 2026-05-12 CN claimed
US-12441741-B2 Ring closing synthesis of macrocyclic MCL-1 inhibitor intermediates AMGEN INC. (US) 2025-10-14 US claimed
US-12435049-B2 Synthesis of vinylic protected alcohol intermediates AMGEN INC. (US) 2025-10-07 US claimed
EP-4585599-A1 NITROGEN-CONTAINING FUSED RING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) 2025-07-16 EP claimed
CN-115745884-B Opioid derivatives, intermediates and process for preparing the same 绍兴赜军生物医药科技有限公司 2025-06-13 CN claimed
EP-4146636-B1 SYNTHESIS OF VINYLIC PROTECTED ALCOHOL INTERMEDIATES AMGEN INC (US) 2025-06-11 EP claimed
US-20250179111-A1 METHOD FOR SYNTHESIZING HIGH-PURITY PLANT-DERIVED CHOLESTEROL EAST CHINA NORMAL UNIVERSITY (CN) 2025-06-05 US claimed
US-20250154177-A1 PYRROLOBENZODIAZEPINE INTERMEDIATES AND USES THEREOF SIGMA-ALDRICH CO. LLC 2025-05-15 US claimed
US-20250145658-A1 SYNTHESIS METHOD FOR HIGH-PURITY CHOLESTEROL EAST CHINA NORMAL UNIVERSITY (CN) 2025-05-08 US claimed
US-5250703-A Glycosidase inhibitors; reducing azido lactone, decyclizing, protective silation, hydrolysis, epoxidation, hydrogenation, deprotecting MONSANTO COMPANY (US) 1993-10-05 US claimed
US-5248761-A Amino acid terminated polyesters having predetermined monomeric sequence UNITED STATES SURGICAL CORPORATION (US) 1993-09-28 US claimed
WO-1993016040-A1 FLUORINE-CONTAINING VITAMIN D3 ANALOGUES DAIKIN INDUSTRIES, LTD. (JP) 1993-08-19 WO claimed
US-5235052-A PROCESS FOR PREPARING SUBSTITUTED CYCLOBUTANE PURINES BRISTOL-MYERS SQUIBB COMPANY (US) 1993-08-10 US claimed
EP-0496160-A1 Synthetic conversion of bryostatin 2 into bryostatin 1 ARIZONA BOARD OF REGENTS (US) 1992-07-29 EP claimed
EP-0452729-A1 Process for preparing substituted cyclobutanes BRISTOL-MYERS SQUIBB COMPANY (US) 1991-10-23 EP claimed
EP-0278368-B1 A METHOD FOR PRODUCING CHLOROSILANES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-19 EP claimed
US-4780556-A Method for producing chlorosilanes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-10-25 US claimed
EP-0278368-A1 A method for producing chlorosilanes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-17 EP claimed
US-4490546-A Process for 4a'(R),5'-dihydromevinolin MERCK & CO., INC. (US) 1984-12-25 US claimed