Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.67 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.67 |
| ▸ | ITGB7 | P26010 | 12/20 | 0.67 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601993 | 0.88 | ITGB1 (0.84) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL13602017 | 0.87 | ITGB1 (0.82) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL11750694 | 0.81 | ITGB1 (0.72) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL13602006 | 0.80 | ITGB1 (0.79) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL13602106 | 0.80 | ITGB1 (1.00) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL8278642 | 0.80 | ITGA4 (0.79) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL13601998 | 0.80 | ITGB1 (0.75) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL13601958 | 0.79 | ITGB1 (0.76) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL14603025 | 0.79 | ITGA4 (0.68) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL14603020 | 0.79 | ITGB1 (0.74) | ITGB1ITGA4ITGB7ITGA5ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113003-A2 | METHOD FOR AUGMENTING B CELL DEPLETION | GENENTECH, INC. (US) | 2005-12-01 | — | — | WO | disclosed |