Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210291 | 0.78 | HSD17B10 (0.50) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL286999 | 0.75 | HSD17B10 (0.47) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27432878 | 0.75 | HSD17B10 (0.47) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10496189 | 0.73 | HSD17B10 (0.46) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL540823 | 0.71 | ALDH1A1 (0.45) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL114334 | 0.71 | MAPT (0.44) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8615319 | 0.69 | HSD17B10 (0.43) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8613502 | 0.69 | ALDH1A1 (0.43) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8829451 | 0.69 | ALDH1A1 (0.41) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8616481 | 0.68 | HSD17B10 (0.37) | HSD17B10MAPTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092899-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2005-10-06 | — | — | WO | disclosed |