Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 5/20 | 0.46 |
| ▸ | CHUK | O15111 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018709 | 0.86 | ALDH1A1 (0.56) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL4883270 | 0.81 | AKT1 (0.55) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL8278261 | 0.79 | SMN1; SMN2 (0.71) | ALDH1A1PKML3MBTL1KDM4EMEN1 | |
| SCHEMBL3036935 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL22516274 | 0.76 | ALDH1A1 (0.70) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL11890646 | 0.76 | MAPT (0.60) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL22516006 | 0.75 | ALDH1A1 (0.72) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL3762091 | 0.75 | ALDH1A1 (0.53) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL3854458 | 0.74 | ALDH1A1 (0.50) | ALDH1A1PKMPTPN2PTPN1PTPN5 | |
| SCHEMBL615643 | 0.73 | ALDH1A1 (0.51) | ALDH1A1PKMBRD4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |